insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Your doctor may recommend medications to help with blood pressure, blood sugar, insulin resistance, lipid lowering and weight management. Madeline Holcombe, CNN Money, 23 Apr. 2025 This visceral fat is strongly linked to insulin resistance, inflammation, and a higher risk of fat accumulation in the liver.1 If a postmenopausal woman doesn’t experience overweight or metabolic syndrome, would her changing hormones still put her at greater risk for MASLD? Claire Bugos, Verywell Health, 7 Apr. 2025 Conditions like insulin resistance, obesity, and cardiovascular disease are linked to higher rates of depression, anxiety, and cognitive decline. Jesse Pines, Forbes.com, 5 Apr. 2025 Instead, the organ triggers insulin resistance within it. Paul Smaglik, Discover Magazine, 21 Mar. 2025 See All Example Sentences for insulin resistance

Word History

First Known Use

1927, in the meaning defined above

Time Traveler
The first known use of insulin resistance was in 1927

Cite this Entry

“Insulin resistance.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/insulin%20resistance. Accessed 9 May. 2025.

Medical Definition

insulin resistance

noun
: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes
Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!